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''Streptomyces clavuligerus'' is a species of Gram-positive bacterium notable for producing clavulanic acid. ''S. clavuligerus'' ATCC 27064 (NRRL 3585, DSM 738) was first described by Higgens and Kastner, who isolated it from a South American soil sample. Its name refers to the shape of its spore-bearing hyphal branches: from the Latin, clavula, meaning ''little club'', and igerus, meaning ''bearing''. ''S. clavuligerus'' spores are gray to grayish-green.〔 ''S. clavuligerus'' produces over 20 secondary metabolites, including many beta-lactam antibiotics such as clavulanic acid, cephamycin C, deacetoxycephalosporin C, penicillin N (an intermediate in cephamycin C pathway), and at least four other clavams. Non-β-lactam antibiotics include holomycin and an antibiotic complex, MM 19290, related to tunicamycin; a beta-lactamase-inhibitory protein (BLIP) has also been described. Another important characteristic of ''S. clavuligerus'' is that it is not able to use glucose as a carbon source because it lacks a glucose transport system. It also possesses all the enzymes of the urea cycle, which is unusual for a prokaryote, although it is not clear whether the urea cycle is functional. == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Streptomyces clavuligerus」の詳細全文を読む スポンサード リンク
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